Research Activities #276, August 2003
نویسنده
چکیده
shown any substantial difference in how coronary artery disease (CAD) patients fare 2 to 3 years after either coronary artery bypass graft (CABG) surgery or percutaneous transluminal coronary angioplasty (PTCA), two procedures that are performed to restore adequate blood supply to blocked arteries. However, a recent meta-analysis performed by researchers at Tufts-New England Medical Center in Boston found that more CABG patients than angioplasty patients were alive 5 years later, and they had less angina (crushing chest pain) and fewer additional revascularization procedures than PTCA patients. Yet, only 35 percent of PTCA patients had stents inserted during the initial procedures. Stents are expandable metal mesh tubes that are inserted during angioplasty, a procedure in which a balloon-tipped catheter is threaded through the blocked coronary artery. The balloon is inflated to flatten plaque against the arterial walls to reestablish cardiac blood flow. Placed at the site of the blockage, the stent pushes against the artery wall to keep it open after the surgery. The addition of stents and newer adjunctive therapies may improve outcomes for PTCA relative to CABG, but long-term data are not yet available, note the researchers who conducted the study. Their work was supported in part by the Agency for Healthcare Research and Quality (HS06503). The meta-analysis involved 13 randomized trials on 7,964 patients comparing PTCA with CABG. The researchers found a 1.9 percent absolute survival advantage favoring CABG over PTCA for all trials at 5 years but no significant advantage at 1, 3, or 8 years. Patients randomized to PTCA had more repeat revascularization procedures at all time points. However, the addition of stents reduced the need for repeat revascularization by about half Highlights
منابع مشابه
Atlantic halibut Hippoglossus hippoglossus : indication of readiness for first feeding
The problem of determining when larvae should be offered food is particularly difficult in a Ž . species such as Atlantic halibut that has a long yolk-sac period 280–320 degree days, dd . In order to help determine at what age Atlantic halibut larvae are able to digest food, we compared the activities of key digestive enzymes in four yolk-sac stages at an age interval that has been recommended ...
متن کاملPurification and Some Properties of Scenedesmus Ferredoxin
A simple procedure for purification of ferredoxin from a green alga, Scenedesmus, is described. Crystalline ferredoxin had an absorption spectrum with maxima at 276, 330, 421, and 464 rnp and with minima at 255, 293, 390, and 445 rnp. The ratios of the optical densities at 421 and 330 rnp to that at 276 rnp were 0.651 and 0.883, respectively. The substance was shown to be pure by disc electroph...
متن کاملPositive Systems, Proceedings of the First Multidisciplinary International Symposium on Positive Systems: Theory and Applications (POSTA 2003), Rome, Italy, August 28-30, 2003
Feel lonely? What about reading books? Book is one of the greatest friends to accompany while in your lonely time. When you have no friends and activities somewhere and sometimes, reading book can be a great choice. This is not only for spending the time, it will increase the knowledge. Of course the b=benefits to take will relate to what kind of book that you are reading. And now, we will conc...
متن کاملPhotochemistry of VOCs and halogens in the MBL
A box model study on photochemical interactions between VOCs and reactive halogen species in the marine boundary layer K. Toyota, Y. Kanaya, M. Takahashi , and H. Akimoto Frontier Research System for Global Change, Yokohama, Japan Also at Center for Climate System Research, The University of Tokyo, Tokyo, Japan Received: 1 August 2003 – Accepted: 28 August 2003 – Published: 1 September 2003 Cor...
متن کامل